Based on the daily precipitation data of 66 meteorological stations in Fujian Province, NCEP/NCAR reanalysis data and NOAA daily OLR data, the large-scale circulation characteristics and it’s variation of drought events in Fujian Province from March to June 2018 were analyzed. The results show that less precipitation in every month, less rainstorm days and weakness of persistent rainstorm process led to severe meteorological drought in Fujian Province from March to June 2018. Affected by the La Niña event, Fujian was in the center of downdraft. The blocking highs were weaker, the West Pacific subtropical high was weaker and moving to the south and the east than usual, Fujian Province was in the anomalous center of water vapor flux divergence, which was the circulation background of drought. The variation of circulation showed that the blocking highs, the subtropical high and the northward propagation of tropical convection were not active in the earlier period, leading to less rainstorm days and drought development. In the later period, the circulation presented the characteristics of periodic oscillation, and the effective cooperation of the north and south system provided favorable circulation conditions for occurrence of persistent rainstorm, which alleviated the drought.